Zavegepant for treating acute migraine

Zavegepant is in clinical development for the acute treatment of migraine. Migraines is a headache that is usually characterised by throbbing in one side of the head. In addition to this, other symptoms include sensitivity to light and sound, nausea and vomiting. The cause of migraines is not known but some triggers include tiredness, anxiety and too much caffeine. Migraines are also thought to be genetic. The two major types are migraine with aura and migraine without aura. Patients experiencing aura can experience problems with sight, numbness and dizziness. Migraine without aura are the most common and usually last 4-72 hours. There remains unmet need in acute migraine treatment such as fast acting relief from pain, and alternatives to oral products that cannot be taken by some patients due to nausea and vomiting.