Tapinarof for treating atopic dermatitis

Tapinarof cream is being developed for the treatment of atopic dermatitis (AD). AD (also known as atopic eczema) is a common skin condition that causes the skin to become itchy, cracked, and dry. In moderate cases, the patches of skin on the body can become large and are associated with intense itching and redness. The cause of AD is not fully known but can be made worse by coming into contact with an allergen, heat, skin infections, stress or hormonal changes. Patients who experience AD can suffer from poor quality of life and other comorbidities such as mental health disorders. Current treatment options for AD have varied effectiveness and significant side effects with long-term use. Some treatments can also only be used on small areas of skin. Therefore, there is a need to develop additional treatment options for these patients.