Semaglutide for weight management

Semaglutide is in clinical development for weight management in adults. Overweight and obesity are typically defined by a body mass index (BMI) over 25 and 30, respectively. While this is commonly caused by excessive calorie intake, overweight and obesity are complex conditions with many other potential multifactorial causes. Obesity increases the risk of developing a range of serious health conditions such as stroke, hypertension and type 2 diabetes. Additionally, quality of life can be affected and lead to psychological problems, such as depression and low self-esteem. Recommendations for treatment include lifestyle changes such as increased exercise, healthy diet and a net calorie deficit, along with help through counselling and medication. There is a need for treatment options that will allow obese or overweight patients to reach their individual treatment goals to improve their health.