Itopride hydrochloride for treating functional dyspepsia

Itopride hydrochloride is being developed for the treatment of functional dyspepsia. Dyspepsia refers to a group of symptoms including upper belly pain, belching, bloating and feeling full. It is also known as indigestion. The oesophagus (gullet), stomach and first part of the small intestine (duodenum) are all affected by dyspepsia symptoms. Functional dyspepsia is long term indigestion with no identifiable cause. Possible causes that can contribute to symptoms include alterations to the variety of bacteria that normally live in the digestive system because of a gut infection. Other factors include stress, lifestyle factors and the emotional response to symptoms. Living with these symptoms can reduce quality of life and have a negative impact on mental health. Most treatments for functional dyspepsia are only partly effective, highlighting the need for more targeted and supportive care.