Finerenone for treating heart failure

Finerenone is currently in clinical development for treating heart failure in adults. Heart failure is a combination of symptoms and signs that indicate that the heart is pumping blood around the body less efficiently. Left ventricular ejection fraction is calculated as the percentage of how much blood in a part of the heart called the left ventricle is pumped out with each contraction. The prevalence of heart failure increases slowly with age until about 65 years of age, and then more rapidly. Symptoms of heart failure include breathlessness, fatigue and swelling caused by excess fluid build-up in bodily tissues. There is an unmet need for well-tolerated treatment options for patients with heart failure.