Eflornithine with lomustine for treating recurrent anaplastic astrocytoma

An anaplastic astrocytoma is a rare cancerous brain tumour that grows from astrocyte brain cells. Anaplastic means the cells divide rapidly and don’t look like normal cells in structure or function. They affect adults and children and are often treated by neurosurgery followed by radiotherapy and sometimes chemotherapy. They’re more common in adults between the ages of 30 and 70 and are more common in males. They are fast growing and often come back following treatment (known as a recurrence) in a more advanced form, so new treatment options are needed.