Dorocubicel for treating haematological malignancies in adults requiring allogeneic HSCT

Haematological cancers also known as blood cancers, occur when abnormal cells in the blood grow out of control. They are usually categorised by site according to whether cancer is first detected in the blood (leukaemias), lymph nodes (lymphomas), or bone (myelomas). The abnormal cells can crowd out normal blood cells, which have important functions in the body. This can make it hard to fight off infections. It can also cause symptoms like breathlessness, tiredness, bruising or bleeding, fever, pain, or lumps in the glands. There is a need for new treatment options as these cancers are life-threatening and often associated with low survival outcomes and high incidence of relapse.