Eosinophilic oesophagitis (EoE) is a chronic disorder of the digestive system in which large numbers of white blood cells called eosinophils are present in the tube that carries food from the mouth to the stomach (oesophagus). Eosinophils play a role in immune regulation. The production and accumulation of eosinophils seen in EoE may be caused by many factors such as immune hypersensitivity responses to foods or environmental allergens. Common symptoms include difficulty swallowing, food getting stuck in the throat, nausea, vomiting, poor growth, weight loss, stomach pain, poor appetite and malnutrition. The available treatment option is limited by side effects and there is evidence to suggest it is only partially effective. This demonstrates an unmet treatment need for patients with EoE.
Cendakimab for eosinophilic oesophagitis in people aged 12 years and over
Eosinophilic oesophagitis (EoE) is a chronic disorder of the digestive system in which large numbers of white blood cells called eosinophils are present in the tube that carries food from the mouth to the stomach (oesophagus). Eosinophils play a role in immune regulation.