Allo-APZ2-CVU for treating chronic venous leg ulcers

Allo-APZ2-CVU is in clinical development for the treatment of therapy-resistant non-healing chronic venous leg ulcers. A leg ulcer is a long-lasting sore that takes more than 2 weeks to heal. It usually develops on the inside of the leg, between the knee and the ankle. Venous leg ulcers are the most common type of leg ulcer and can develop after a minor injury, if persistently high pressure in the veins of the legs has weakened the skin. The symptoms of a venous leg ulcer include pain, itching and swelling in the affected leg. Treatment usually involved cleaning and dressing the wound and compression therapy to improve blood flow in the leg. But unless the underlying cause of the ulcer is addressed, there is a high risk of a venous leg ulcer coming back after treatment.