Search All Tech Briefings

Search technology briefings produced by NIHR Innovation Observatory. These are short reports on new or repurposed medicines that we have already sent to our stakeholders. Only those technologies (medicines) that are within the scope of our stakeholders will have a technology briefing available. Search our technology briefings by intervention (drug or device), specific indication (disease or condition), or general therapeutic area.

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Title	Intervention	Indication	Therapeutic Area	Year	Actions
Selpercatinib for metastatic RET fusion-positive non-small cell lung cancer	Selpercatinib (LOXO-292; LY3527723)	Non-small-cell lung cancer (NSCLC)	Lung and Respiratory Cancer	2019	View \| Download
Selpercatinib for previously untreated advanced RET fusion-positive non-small cell lung cancer	Selpercatinib (LOXO-292; LY3527723)	Non-small-cell lung cancer (NSCLC)	Lung and Respiratory Cancer	2021	View \| Download
Selpercatinib for previously untreated advanced RET-fusion positive thyroid cancer	Selpercatinib (LOXO-292; LY3527723)	Thyroid cancer	Oncology	2022	View \| Download
Selpercatinib for previously untreated medullary thyroid cancer with RET mutation in patients ages 12 and older	Selpercatinib (LOXO-292; LY3527723)	Medullary thyroid cancer (MTC)	Head and Neck Cancer	2022	View \| Download
Selpercatinib for treating advanced solid tumours with RET gene fusion in people aged 12 years and older	Selpercatinib (LOXO-292; LY3527723)	Non-small-cell lung cancer (NSCLC)	Lung and Respiratory Cancer	2023	View \| Download
Selumetinib (granule formulation) for treating neurofibromas type 1-related symptomatic, inoperable plexiform in children	Selumetinib (AZD6244; ARRY-142886)	Plexiform neurofibromas	Nephrology , Neurological Cancer	2024	View \| Download
Selumetinib for neurofibromatosis type 1	Selumetinib (AZD6244; ARRY-142886)	Neurofibromatosis	Neurology	2019	View \| Download
Selumetinib for treating symptomatic, inoperable plexiform neurofibromas associated with type 1 neurofibromatosis in adults	Selumetinib (AZD6244; ARRY-142886)	Plexiform neurofibromas	Neurological Cancer , Neurology	2023	View \| Download
Semaglutide for non-cirrhotic non-alcoholic steatohepatitis	Semaglutide (Ozempic)	Non-alcoholic steatohepatitis (NASH)	Hepatology	2023	View \| Download
Semaglutide for overweight individuals	ATB200/AT2221 , Semaglutide (Ozempic)	Obesity , Weight management	Endocrine Nutritional and Metabolic Disorders	2020	View \| Download