Search All Tech Briefings

Search technology briefings produced by NIHR Innovation Observatory. These are short reports on new or repurposed medicines that we have already sent to our stakeholders. Only those technologies (medicines) that are within the scope of our stakeholders will have a technology briefing available. Search our technology briefings by intervention (drug or device), specific indication (disease or condition), or general therapeutic area.

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Title	Intervention	Indication	Therapeutic Area	Year	Actions
Dabigatran Etexilate (Pradaxa) for Secondary Stroke Prevention in Patients with Embolic Stroke of Undetermined Source – First Line	Dabigatran etexilate (Pradaxa)	Ischaemic stroke	Cardiovascular System	2017	View \| Download
Cysteamine bitartrate for cystic fibrosis exacerbations	Cysteamine bitartrate (Procysbi; RP103; Lynovex; NM001; Cystadrops; Mercaptamine)	Cystic fibrosis	Genetic Disorders , Respiratory System	2018	View \| Download
Cysteamine bitartrate (Procysbi) delayed release for Huntington’s Disease	Cysteamine bitartrate (Procysbi; RP103; Lynovex; NM001; Cystadrops; Mercaptamine)	Huntington's disease	Genetic Disorders , Neurology	2017	View \| Download
CTX001 for transfusion-dependent beta-thalassaemia	CTX001	Beta thalassemia	Genetic Disorders , Haematology	2021	View \| Download
CTX001 for severe sickle cell disease	CTX001	Leukocyte adhesion deficiency , Sickle cell disease (SCD)	Haematology , Immunology	2021	View \| Download
Crovalimab for treatment of paroxysmal nocturnal haemoglobinuria	Crovalimab	Paroxysmal nocturnal haemoglobinuria (PNH)	Haematology	2022	View \| Download
Crizotinib for paediatric ALK-positive anaplastic large cell lymphoma or inflammatory myofibroblastic tumour	Crizotinib (Xalkori; PF-02341066; Xalkor)	Anaplastic large cell lymphoma (ALCL) , Myofibroblastic tumour	Haematological Cancer and Lymphomas	2021	View \| Download
Crizotinib (Xalcori) for locally advanced or metastatic Non‐Small Cell Lung Cancer (NSCLC)	Crizotinib (Xalkori; PF-02341066; Xalkor)	Non-small-cell lung cancer (NSCLC)	Lung and Respiratory Cancer	2018	View \| Download
Crizanlizumab for the prevention of recurrent vaso-occlusive crises in children with sickle cell disease	Crizanlizumab (SEG101; Adakveo)	Sickle cell disease (SCD)	Haematology	2022	View \| Download
Crizanlizumab (formerly SelG1) for Sickle Cell Disease	Crizanlizumab (SEG101; Adakveo)	Sickle cell anaemia	Haematology	2017	View \| Download