Search All Tech Briefings

Search technology briefings produced by NIHR Innovation Observatory. These are short reports on new or repurposed medicines that we have already sent to our stakeholders. Only those technologies (medicines) that are within the scope of our stakeholders will have a technology briefing available. Search our technology briefings by intervention (drug or device), specific indication (disease or condition), or general therapeutic area.

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Title	Intervention	Indication	Therapeutic Area	Year	Actions
Daratumumab (Darzalex) with lenalidomide and dexamethasone for multiple myeloma – first line	Daratumumab (Darzalex; JNJ-54767414) , Dexamethasone (dexamethasone sodium metasulfobenzoate) , Lenalidomide (Revlimid)	Multiple myeloma (MM)	Haematological Cancer and Lymphomas	2017	View \| Download
Dapsone for treating COVID-19	Dapsone (PULM-001;Pulmonem)	COVID-19	Respiratory System	2023	View \| Download
Daprodustat for anaemia associated with chronic kidney disease	Daprodustat (GSK1278863)	Anaemia	Cardiovascular System , Haematology , Nephrology	2021	View \| Download
Dapagliflozin for heart failure with preserved ejection fraction	Dapagliflozin (Forxiga; BMS512148; Farxiga; dapagliflozin propanediol monohydrate)	Heart failure (HF)	Cardiovascular System	2019	View \| Download
Dapagliflozin for chronic kidney disease	Dapagliflozin (Forxiga; BMS512148; Farxiga; dapagliflozin propanediol monohydrate)	Chronic kidney disease (CKD)	Cardiovascular System , Nephrology	2020	View \| Download
Dapagliflozin for chronic heart failure with reduced ejection fraction	Dapagliflozin (Forxiga; BMS512148; Farxiga; dapagliflozin propanediol monohydrate)	Heart failure (HF)	Cardiovascular System	2019	View \| Download
Danicopan with eculizumab or ravulizumab for treating paroxysmal nocturnal haemoglobinuria	Danicopan (ACH-0144471; ACH-4471; ALXN2040) , Ravulizumab (ALXN1210; Ultomiris)	Paroxysmal nocturnal haemoglobinuria (PNH)	Haematology	2022	View \| Download
Dabrafenib with Trametinib with adjuvant therapy for treating advanced BRAF V600 mutation-positive melanoma in adolescents	Dabrafenib (Tafinlar; GSK2118436; dabrafenib mesilate) , Trametinib (Mekinist; TMT212; GSK-1120212B; GSK1120212; JTP-74057; trametinib dimethyl sulfoxide)	Melanoma	Skin Cancer	2023	View \| Download
Dabrafenib with trametinib for treating paediatric BRAF V600 mutated high-grade or low-grade glioma	Dabrafenib (Tafinlar; GSK2118436; dabrafenib mesilate) , Trametinib (Mekinist; TMT212; GSK-1120212B; GSK1120212; JTP-74057; trametinib dimethyl sulfoxide)	Glioma	Neurological Cancer	2022	View \| Download
Dabrafenib with trametinib for treating metastatic or unresectable BRAF V600 mutation-positive melanoma in adolescents	Dabrafenib (Tafinlar; GSK2118436; dabrafenib mesilate) , Trametinib (Mekinist; TMT212; GSK-1120212B; GSK1120212; JTP-74057; trametinib dimethyl sulfoxide)	Melanoma	Skin Cancer	2023	View \| Download