Search All Tech Briefings

Search technology briefings produced by NIHR Innovation Observatory. These are short reports on new or repurposed medicines that we have already sent to our stakeholders. Only those technologies (medicines) that are within the scope of our stakeholders will have a technology briefing available. Search our technology briefings by intervention (drug or device), specific indication (disease or condition), or general therapeutic area.

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Title	Intervention	Indication	Therapeutic Area	Year	Actions
Pembrolizumab-vibostolimab for previously untreated non-small-cell lung cancer (NSCLC)	Pembrolizumab-vibostolimab (MK-7684; MK7684A; Vibostolimab)	Non-small-cell lung cancer (NSCLC)	Lung and Respiratory Cancer	2023	View \| Download
Pembrolizumab-vibostolimab with etoposide and platinum chemotherapy for previously untreated extensive-stage small cell lung cancer	Etoposide , Pembrolizumab-vibostolimab (MK-7684; MK7684A; Vibostolimab) , Platinum-based chemotherapy	Small-cell lung cancer (SCLC)	Lung and Respiratory Cancer	2023	View \| Download
Pemigatinib for locally advanced or metastatic, relapsed or refractory cholangiocarcinoma with FGFR2 fusion or rearrangement	Pemigatinib (INCB054828)	Cholangiocarcinoma	Gastrointestinal Cancer	2019	View \| Download
Pemigatinib for treating myeloproliferative neoplasms with FGFR1 rearrangement	Pemigatinib (INCB054828)	Myeloproliferative Neoplasms	Haematological Cancer and Lymphomas	2022	View \| Download
Pentetrazol for Idiopathic Hypersomnia and Narcolepsy Type 2	Pentetrazol (BTD-001)	Hypersomnia , Narcolepsy	Neurology	2018	View \| Download
Pentosan polysulfate sodium (Elmiron) for bladder pain syndrome (interstitial cystitis)	Pentosan polysulphate sodium (Elmiron; AK-150)	Bladder pain syndrome , Interstitial cystitis , Painful bladder syndrome	Nephrology , Urology	2017	View \| Download
Perampanel (Fycompa) for Paediatric Epilepsy	Perampanel (Fycompa; E 2007; ER-155055-90)	Epilepsy	Neurology	2018	View \| Download
Pertuzumab and trastuzumab (fixed-dose combination) in addition to chemotherapy for breast cancer	Pertuzumab and Trastuzumab (Phesgo; RO7198574) (fixed dose combination: Trastuzumab; Pertuzumab)	Breast cancer	Breast Cancer	2019	View \| Download
Pertuzumab biosimilar with trastuzumab and chemotherapy neoadjuvant and adjuvant therapy for early stage and locally advanced HER2-positive breast cancer	Chemotherapy , Pertuzumab biosimilar , Trastuzumab (Herceptin; RG-597)	Breast cancer	Breast Cancer	2024	View \| Download
Pevonedistat in addition to azacitidine for Higher-Risk Myelodysplastic Syndromes, Chronic Myelomonocytic Leukemia and Low Blast Acute Myeloid Leukemia – first-line	Azacitidine (Vidaza; CC-486) , Pevonedistat (MLN-4924; TAK-924)	Acute myeloid leukaemia (AML) , Chronic myelomonocytic leukaemia (CMML) , Myelodysplastic syndrome (MDS)	Haematological Cancer and Lymphomas	2020	View \| Download