Search All Tech Briefings

Search technology briefings produced by NIHR Innovation Observatory. These are short reports on new or repurposed medicines that we have already sent to our stakeholders. Only those technologies (medicines) that are within the scope of our stakeholders will have a technology briefing available. Search our technology briefings by intervention (drug or device), specific indication (disease or condition), or general therapeutic area.

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Title	Intervention	Indication	Therapeutic Area	Year	Actions
Pembrolizumab perioperative therapy with neoadjuvant chemotherapy for treating cisplatin eligible muscle-invasive bladder cancer	Chemotherapy , Pembrolizumab (Keytruda; MK-3475)	Bladder cancer	Urological Cancer	2022	View \| Download
Pembrolizumab plus chemotherapy for the treatment of gastric cancer or gastro-oesophageal junction cancer – First Line	Pembrolizumab (Keytruda; MK-3475)	Gastric cancer , Gastro-oesophageal junction cancer	Gastrointestinal Cancer	2021	View \| Download
Pembrolizumab with Bacillus Calmette-Guerin for treating high-risk non-muscle invasive bladder cancer	Bacillus Calmette-Guerin (BCG; BCG Tokyo-172; OncoTICE) , Pembrolizumab (Keytruda; MK-3475)	Bladder cancer	Urological Cancer	2023	View \| Download
Pembrolizumab with chemoradiotherapy for treating high-risk locally advanced cervical cancer	Chemoradiotherapy , Pembrolizumab (Keytruda; MK-3475)	Cervical cancer	Female Reproductive Cancer	2022	View \| Download
Pembrolizumab with chemotherapy for HR+/HER2- locally recurrent inoperable or metastatic breast cancer	Chemotherapy , Pembrolizumab (Keytruda; MK-3475)	Breast cancer	Breast Cancer	2023	View \| Download
Pembrolizumab with chemotherapy for platinum-resistant recurrent ovarian cancer after 1 or 2 therapies	Chemotherapy , Pembrolizumab (Keytruda; MK-3475)	Ovarian cancer	Female Reproductive Cancer	2023	View \| Download
Pembrolizumab with chemotherapy for treating advanced or recurrent endometrial cancer	Chemotherapy , Pembrolizumab (Keytruda; MK-3475)	Endometrial cancer	Female Reproductive Cancer	2023	View \| Download
Pembrolizumab with Enzalutamide and androgen deprivation therapy for the treatment of metastatic hormone sensitive prostate cancer	Androgen deprivation therapy , Enzalutamide (Xtandi; MDV3100) , Pembrolizumab (Keytruda; MK-3475)	Prostate cancer	Male Reproductive Cancer	2022	View \| Download
Pembrolizumab with enzalutamide for treating metastatic castration-resistant prostate cancer	Enzalutamide (Xtandi; MDV3100) , Pembrolizumab (Keytruda; MK-3475)	Prostate cancer	Male Reproductive Cancer	2022	View \| Download
Pembrolizumab with Lenvatinib and chemotherapy for previously untreated advanced or metastatic gastroesophageal adenocarcinoma	Chemotherapy , Lenvatinib (Kisplyx; E7080; lenvatinib mesilate) , Pembrolizumab (Keytruda; MK-3475)	Gastroesophageal adenocarcinoma	Gastrointestinal Cancer	2023	View \| Download