Search All Tech Briefings

Search technology briefings produced by NIHR Innovation Observatory. These are short reports on new or repurposed medicines that we have already sent to our stakeholders. Only those technologies (medicines) that are within the scope of our stakeholders will have a technology briefing available. Search our technology briefings by intervention (drug or device), specific indication (disease or condition), or general therapeutic area.

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Title	Intervention	Indication	Therapeutic Area	Year	Actions
Encorafenib with binimetinib for treating metastatic BRAF V600E mutant non-small-cell lung cancer	Binimetinib (MEK162; MEK-162; ARRY-162) , Encorafenib (LGX818)	Non-small-cell lung cancer (NSCLC)	Lung and Respiratory Cancer	2022	View \| Download
Encorafenib with binimetinib for treating metastatic BRAF V600 mutant non-small-cell lung cancer	Binimetinib (MEK162; MEK-162; ARRY-162) , Encorafenib (LGX818)	Non-small-cell lung cancer (NSCLC)	Lung and Respiratory Cancer	2023	View \| Download
Encorafenib in combination with binimetinib and cetuximab for BRAF V600E mutant metastatic colorectal cancer	Binimetinib (MEK162; MEK-162; ARRY-162) , Cetuximab (Erbitux; STI-001) , Encorafenib (LGX818)	Colorectal cancer	Gastrointestinal Cancer , Oncology	2019	View \| Download
Enasidenib for Relapsed or Refractory Acute Myeloid Leukaemia (AML) with an Isocitrate Dehydrogenase 2 (IDH2) Mutation	Enasidenib (Idhifa; AG-221; CC-90007)	Acute myeloid leukaemia (AML)	Haematological Cancer and Lymphomas	2018	View \| Download
Empagliflozin with linagliptin for treating type 2 diabetes mellitus in children and adolescents	Empagliflozin (Jardiance; DINAMO) , Linagliptin	Type 2 diabetes	Endocrine Nutritional and Metabolic Disorders	2022	View \| Download
Empagliflozin for treatment of chronic heart failure with reduced ejection fraction	Empagliflozin (Jardiance; DINAMO)	Heart failure (HF)	Cardiovascular System	2020	View \| Download
Empagliflozin for treating chronic kidney disease	Empagliflozin (Jardiance; DINAMO)	Chronic kidney disease (CKD)	Cardiovascular System , Nephrology	2022	View \| Download
Empagliflozin for the treatment of acute myocardial infarction to reduce heart failure and mortality	Empagliflozin (Jardiance; DINAMO)	Heart failure (HF)	Cardiovascular System	2022	View \| Download
Empagliflozin for Chronic Heart Failure with Preserved Ejection Fraction	Empagliflozin (Jardiance; DINAMO)	Heart failure (HF)	Cardiovascular System	2021	View \| Download
Emicizumab for mild or moderate haemophilia A	Emicizumab (Hemlibra)	Haemophilia A	Haematology	2021	View \| Download