Search All Tech Briefings

Search technology briefings produced by NIHR Innovation Observatory. These are short reports on new or repurposed medicines that we have already sent to our stakeholders. Only those technologies (medicines) that are within the scope of our stakeholders will have a technology briefing available. Search our technology briefings by intervention (drug or device), specific indication (disease or condition), or general therapeutic area.

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Title	Intervention	Indication	Therapeutic Area	Year	Actions
Ivacaftor for cystic fibrosis in infants	Ivacaftor (Kalydeco; VX-770)	Cystic fibrosis	Genetic Disorders , Respiratory System	2023	View \| Download
Leriglitazone for X-linked andrenoleukodystrophy	Leriglitazone (MIN-102)	X-linked adrenoleukodystrophy (X-ALD)	Endocrine Nutritional and Metabolic Disorders , Genetic Disorders , Neurology	2023	View \| Download
Letermovir for preventing cytomegalovirus in children and adolescents following allogeneic haematopoietic stem cell transplant	Letermovir	Cytomegalovirus (CMV)	Infectious Disease	2023	View \| Download
Leukocyte interleukin with cyclophosphamide, indomethacin, and zinc for neoadjuvant therapy of squamous cell carcinoma of the head and neck	Cyclophosphamide (Procytox; cyclophosphamide monohydrate) , Leukocyte interleukin (CS001P3; Multikine)	Head and neck cancer , Squamous cell carcinoma (SCC)	Head and Neck Cancer	2023	View \| Download
Linerixibat for treating pruritus associated with primary biliary cholangitis	Linerixibat	Pruritus	Dermatology , Hepatology	2023	View \| Download
Linzagolix for treating endometriosis-associated pain	Linzagolix choline	Endometriosis-associated pain	Gynaecology and Obstetrics , Pain Relief	2023	View \| Download
Liposomal cyclosporine A for treating bronchiolitis obliterans syndrome after lung transplant	Liposomal Cyclosporin A (L-CsA)	Bronchiolitis obliterans	Respiratory System	2023	View \| Download
Lurbinectedin with atezolizumab maintenance therapy for extensive-stage small-cell lung cancer	Atezolizumab (Tecentriq; MPDL3280A) , Lurbinectedin (PM01183; Zepzelca)	Small-cell lung cancer (SCLC)	Lung and Respiratory Cancer	2023	View \| Download
Lutetium oxodotreotide with octreotide for treating previously untreated advanced gastroenteropancreatic neuroendocrine tumour	Lutetium oxodotreotide , Octreotide	Gastroenteropancreatic neuroendocrine tumour	Neurological Cancer	2023	View \| Download
Maralixibat chloride for Progressive familial intrahepatic cholestasis	Maralixibat chloride (SHP625)	Progressive familial intrahepatic cholestasis (PFIC)	Genetic Disorders , Hepatology	2023	View \| Download