Search All Tech Briefings

Search technology briefings produced by NIHR Innovation Observatory. These are short reports on new or repurposed medicines that we have already sent to our stakeholders. Only those technologies (medicines) that are within the scope of our stakeholders will have a technology briefing available. Search our technology briefings by intervention (drug or device), specific indication (disease or condition), or general therapeutic area.

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Title	Intervention	Indication	Therapeutic Area	Year	Actions
OTL-200 for Metachromatic Leukodystrophy	OTL-200 (GSK-2696274)	Metachromatic leukodystrophy (MLD)	Endocrine Nutritional and Metabolic Disorders , Genetic Disorders	2019	View \| Download
Oxybutynin hydrochloride for treating neurogenic detrusor overactivity	Oxybutynin hydrochloride (Vesoxx)	Neurogenic detrusor overactivity	Neurology , Urology	2022	View \| Download
Ozanimod for moderate to severe ulcerative colitis	Ozanimod (RPC1063; Zeposia; ozanimod hydrochloride)	Ulcerative colitis	Gastroenterology	2020	View \| Download
Paclitaxel with Encequidar for advanced breast cancer	Encequidar (HM-30181) , Paclitaxel (Taxol; paclitaxel albumin)	Breast cancer	Breast Cancer	2022	View \| Download
Palbociclib for breast cancer - post neoadjuvant therapy	Palbociclib (Ibrance; PD-0332991)	Breast cancer	Breast Cancer	2020	View \| Download
Palbociclib with trastuzumab with or without pertuzumab and endocrine therapy for HR+/HER2+ metastatic breast cancer	Palbociclib (Ibrance; PD-0332991) , Trastuzumab (Herceptin; RG-597)	Breast cancer	Breast Cancer	2023	View \| Download
Palovarotene for episodic and chronic use in fibrodysplasia ossificans progressiva – first line	Palovarotene (RG-667)	Fibrodysplasia ossificans progressiva	Musculoskeletal System	2019	View \| Download
Palovarotene for flare-ups in fibrodysplasia ossificans progressiva – first line	Palovarotene (RG-667)	Fibrodysplasia ossificans progressiva	Musculoskeletal System	2019	View \| Download
Pariglasgene brecaparvovec for treating glycogen storage disease type 1a	Pariglasgene brecaparvovec	Glycogen storage disease type 1a	Endocrine Nutritional and Metabolic Disorders	2023	View \| Download
Parsaclisib for marginal zone lymphoma – relapsed or refractory	Parsaclisib (INCB050465)	Marginal zone lymphoma (MZL)	Haematological Cancer and Lymphomas	2021	View \| Download