Search All Tech Briefings

Search technology briefings produced by NIHR Innovation Observatory. These are short reports on new or repurposed medicines that we have already sent to our stakeholders. Only those technologies (medicines) that are within the scope of our stakeholders will have a technology briefing available. Search our technology briefings by intervention (drug or device), specific indication (disease or condition), or general therapeutic area.

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Title	Intervention	Indication	Therapeutic Area	Year	Actions
Lenvatinib in combination with pembrolizumab for advanced/unresectable hepatocellular carcinoma – first-line	Lenvatinib (Kisplyx; E7080; lenvatinib mesilate) , Pembrolizumab (Keytruda; MK-3475)	Hepatocellular carcinoma (HCC)	Gastrointestinal Cancer	2021	View \| Download
Lenvatinib in combination with Pembrolizumab for advanced or recurrent endometrial cancer - First Line	Lenvatinib (Kisplyx; E7080; lenvatinib mesilate) , Pembrolizumab (Keytruda; MK-3475)	Endometrial cancer	Female Reproductive Cancer	2021	View \| Download
Lenvatinib in combination with pembrolizumab for advanced endometrial cancer – second line	Lenvatinib (Kisplyx; E7080; lenvatinib mesilate) , Pembrolizumab (Keytruda; MK-3475)	Endometrial cancer	Female Reproductive Cancer	2020	View \| Download
Lenvatinib in addition to everolimus or pembrolizumab for advanced renal cell carcinoma – First line	Everolimus (Zortress; RAD001; Afinitor; Certican; RAD-001) , Lenvatinib (Kisplyx; E7080; lenvatinib mesilate) , Pembrolizumab (Keytruda; MK-3475)	Renal cell carcinoma (RCC)	Renal Cancer	2020	View \| Download
Lenvatinib and pembrolizumab with transarterial chemoembolisation for treating hepatocellular carcinoma	Lenvatinib (Kisplyx; E7080; lenvatinib mesilate) , Pembrolizumab (Keytruda; MK-3475)	Hepatocellular carcinoma (HCC)	Gastrointestinal Cancer	2022	View \| Download
Lenti‐D for adrenoleukodystrophy in boys	Elivaldogene tavalentivec (Lenti-D)	Adrenoleukodystrophy (ALD)	Genetic Disorders , Neurology	2017	View \| Download
Leniolisib for previously untreated activated phosphoinositide 3-kinase delta syndrome	Leniolisib	Activated PI3K delta syndrome	Genetic Disorders	2022	View \| Download
Lenalidomide in addition to R-CHOP chemotherapy for diffuse large B-cell lymphoma	Lenalidomide (Revlimid) , R-CHOP	Diffuse large B-cell lymphoma (DLBCL)	Haematological Cancer and Lymphomas	2019	View \| Download
Lenalidomide (Revlimid) in combination with rituximab for untreated follicular lymphoma	Lenalidomide (Revlimid) , Rituximab (MabThera; Rituxan; RG 105)	Follicular lymphoma	Haematological Cancer and Lymphomas	2017	View \| Download
Lenalidomide (Revlimid) for Newly Diagnosed Multiple Myeloma – First Line	Lenalidomide (Revlimid)	Multiple myeloma (MM)	Haematological Cancer and Lymphomas	2017	View \| Download