Search All Tech Briefings

Search technology briefings produced by NIHR Innovation Observatory. These are short reports on new or repurposed medicines that we have already sent to our stakeholders. Only those technologies (medicines) that are within the scope of our stakeholders will have a technology briefing available. Search our technology briefings by intervention (drug or device), specific indication (disease or condition), or general therapeutic area.

| 1184 Results

Clear All Filters

Title	Intervention	Indication	Therapeutic Area	Year	Actions
Niraparib for metastatic castration-resistant prostate cancer with DNA-repair anomalies	Niraparib (Zejula; MK 4827; JNJ 64091742; GSK 3985771; niraparib tosylate monohydrate)	Prostate cancer	Male Reproductive Cancer	2020	View \| Download
Niraparib with abiraterone acetate and prednisone for metastatic castration resistant prostate cancer	Abiraterone acetate (Zytiga; Yonsa) , Niraparib (Zejula; MK 4827; JNJ 64091742; GSK 3985771; niraparib tosylate monohydrate) , Prednisone (Decadron; Lodotra)	Prostate cancer	Male Reproductive Cancer	2022	View \| Download
Niraparib with abiraterone acetate and prednisone for treating homologous recombination repair-mutated metastatic castration-sensitive prostate cancer	Abiraterone acetate (Zytiga; Yonsa) , Niraparib (Zejula; MK 4827; JNJ 64091742; GSK 3985771; niraparib tosylate monohydrate) , Prednisone (Decadron; Lodotra)	Prostate cancer	Male Reproductive Cancer	2024	View \| Download
Niraparib with pembrolizumab maintenance therapy for metastatic stage III or IV non-small cell lung cancer	Niraparib (Zejula; MK 4827; JNJ 64091742; GSK 3985771; niraparib tosylate monohydrate) , Pembrolizumab (Keytruda; MK-3475)	Non-small-cell lung cancer (NSCLC)	Lung and Respiratory Cancer	2023	View \| Download
Nirogacestat for treating desmoid tumours	Nirogacestat (PF-3084014;Ogsiveo)	Desmoid Tumour	Musculoskeletal System	2024	View \| Download
Nitazoxanide for treatment of common cold due to rhinovirus or other enterovirus infection	Nitazoxanide (NT-300; NTZ; PH-5776)	Common cold	Infectious Disease	2021	View \| Download
Nitisinone for Alkaptonuria	Nitisinone (Orfadin; SYN118)	Alkaptonuria	Endocrine Nutritional and Metabolic Disorders , Genetic Disorders	2019	View \| Download
Nivolumab (Opdivo) + Ipilimumab (Yervoy) for metastatic colorectal cancer patients with deficient DNA mismatch repair mechanism (dMMR) or high microsatellite instability (MSI-H)	Ipilimumab (Yervoy; BMS 734016; MDX 101) , Nivolumab (Opdivo; BMS-936558; ONO-4538)	Colon cancer	Gastrointestinal Cancer	2017	View \| Download
Nivolumab (Opdivo) for Melanoma after complete resection of Stage IIIb/c or Stage IV Melanoma (adjuvant therapy)	Nivolumab (Opdivo; BMS-936558; ONO-4538)	Melanoma	Skin Cancer	2017	View \| Download
Nivolumab (Opdivo) for Oesophageal Cancer	Nivolumab (Opdivo; BMS-936558; ONO-4538)	Oesophageal cancer	Head and Neck Cancer	2017	View \| Download