Search All Tech Briefings

Search technology briefings produced by NIHR Innovation Observatory. These are short reports on new or repurposed medicines that we have already sent to our stakeholders. Only those technologies (medicines) that are within the scope of our stakeholders will have a technology briefing available. Search our technology briefings by intervention (drug or device), specific indication (disease or condition), or general therapeutic area.

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Title	Intervention	Indication	Therapeutic Area	Year	Actions
Daratumumab in addition to bortezomib, lenalidomide and dexamethasone for multiple myeloma – first line	Bortezomib (Velcade; bortezomib mannitol boronic ester) , Daratumumab (Darzalex; JNJ-54767414) , Dexamethasone (dexamethasone sodium metasulfobenzoate) , Lenalidomide (Revlimid)	Multiple myeloma (MM)	Haematological Cancer and Lymphomas	2020	View \| Download
Daratumumab in addition to cyclophosphamide, bortezomib and dexamethasone for newly diagnosed systemic amyloid light-chain amyloidosis	Bortezomib (Velcade; bortezomib mannitol boronic ester) , Cyclophosphamide (Procytox; cyclophosphamide monohydrate) , Daratumumab (Darzalex; JNJ-54767414) , Dexamethasone (dexamethasone sodium metasulfobenzoate)	Amyloidosis	Endocrine Nutritional and Metabolic Disorders	2020	View \| Download
Daratumumab in addition to pomalidomide and dexamethasone for relapsed or refractory multiple myeloma	Daratumumab (Darzalex; JNJ-54767414) , Dexamethasone (dexamethasone sodium metasulfobenzoate) , Pomalidomide (Imnovid; CC-4047; Pomalyst)	Multiple myeloma (MM)	Haematological Cancer and Lymphomas	2020	View \| Download
Daridorexant for Insomnia	Daridorexant (ACT-541468; Nemorexant)	Insomnia	Neurology	2020	View \| Download
Deferiprone for transfusional iron overload in sickle cell disease and other anaemias – First Line	Deferiprone (Ferriprox)	Iron overload	Endocrine Nutritional and Metabolic Disorders , Haematology	2020	View \| Download
DermaSys for erectile dysfunction	Glyceryl Trinitrate (MED2002; MED2005; Eroxon; DermaSys)	Erectile dysfunction	Men's Health	2020	View \| Download
Difelikefalin for pruritus associated with chronic kidney disease	Difelikefalin (Korsuva; CR845)	Pruritus	Cardiovascular System , Dermatology , Nephrology	2020	View \| Download
Durvalumab for advanced, EGFR/ALK wild-type, high PD-L1 expression, non-small cell lung cancer- first line	Durvalumab (Imfinzi; MEDI4736; MEDI-4736; MEDI 4736)	Non-small-cell lung cancer (NSCLC)	Lung and Respiratory Cancer	2020	View \| Download
Durvalumab in addition to platinum based chemoradiation therapy for treating non-small-cell lung cancer	Durvalumab (Imfinzi; MEDI4736; MEDI-4736; MEDI 4736)	Non-small-cell lung cancer (NSCLC)	Lung and Respiratory Cancer	2020	View \| Download
Durvalumab in combination with tremelimumab and chemotherapy for unresectable, locally advanced or metastatic urothelial cancer	Durvalumab (Imfinzi; MEDI4736; MEDI-4736; MEDI 4736) , Tremelimumab (CP-675206; CP-675 206)	Bladder cancer	Urological Cancer	2020	View \| Download