Search All Tech Briefings

Search technology briefings produced by NIHR Innovation Observatory. These are short reports on new or repurposed medicines that we have already sent to our stakeholders. Only those technologies (medicines) that are within the scope of our stakeholders will have a technology briefing available. Search our technology briefings by intervention (drug or device), specific indication (disease or condition), or general therapeutic area.

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Title	Intervention	Indication	Therapeutic Area	Year	Actions
Letetresgene autoleucel for treating synovial sarcoma and myxoid round cell liposarcoma	Letetresgene autoleucel	Myxoid round cell liposarcoma , Synovial sarcoma	Sarcoma	2022	View \| Download
Leukocyte interleukin with cyclophosphamide, indomethacin, and zinc for neoadjuvant therapy of squamous cell carcinoma of the head and neck	Cyclophosphamide (Procytox; cyclophosphamide monohydrate) , Leukocyte interleukin (CS001P3; Multikine)	Head and neck cancer , Squamous cell carcinoma (SCC)	Head and Neck Cancer	2023	View \| Download
Leuprorelin acetate for advanced breast cancer in pre or perimenopausal women – adjuvant	Leuprorelin acetate (Prostap DCS; Prostap Depot)	Breast cancer	Breast Cancer	2018	View \| Download
Leuprorelin acetate for the preservation of ovarian function in premenopausal women with neoplastic disease undergoing chemotherapy	Leuprorelin acetate (Prostap DCS; Prostap Depot)	Ovarian function	Breast Cancer , Gynaecology and Obstetrics	2018	View \| Download
Leuprorelin acetate in addition to tamoxifen or an aromatase inhibitor for ER-positive early stage breast cancer in premenopausal women - adjuvant	Leuprorelin acetate (Prostap DCS; Prostap Depot) , Tamoxifen	Breast cancer	Breast Cancer	2018	View \| Download
Levodopa, carbidopa monohydrate and entacapone intestinal gel for severe motor fluctuations in advanced Parkinson’s Disease	Carbidopa (carbidopa monohydrate) , Entacapone (Comtess; OR-611) , Levodopa (ND0612; Inbrija; CVT-30)	Parkinson's disease	Neurology	2021	View \| Download
Levosimendan for respiratory function in amyotrophic lateral sclerosis	Levosimendan (OR1259; Simdax; Leximda)	Respiratory dysfunction	Neurology , Respiratory System	2020	View \| Download
Lifileucel for unresectable or metastatic melanoma – second-line or greater	Lifileucel (Contego; LN-144) IB	Melanoma	Skin Cancer	2020	View \| Download
Ligelizumab for chronic spontaneous urticaria	Ligelizumab (QGE 031)	Chronic spontaneous urticaria (CSU)	Dermatology	2021	View \| Download
Linaclotide acetate for treating Chronic idiopathic constipation	Linaclotide acetate (MD-1100; Constella)	Chronic idiopathic constipation (CIC)	Gastroenterology	2024	View \| Download