Search All Tech Briefings

Search technology briefings produced by NIHR Innovation Observatory. These are short reports on new or repurposed medicines that we have already sent to our stakeholders. Only those technologies (medicines) that are within the scope of our stakeholders will have a technology briefing available. Search our technology briefings by intervention (drug or device), specific indication (disease or condition), or general therapeutic area.

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Title	Intervention	Indication	Therapeutic Area	Year	Actions
KTE-C19 for Relapsed/Refractory B-precursor Acute Lymphocytic Leukaemia in Adults	Brexucabtagene autoleucel (Tecartus; KTE-X19)	Acute lymphoblastic leukaemia (ALL)	Haematological Cancer and Lymphomas	2018	View \| Download
L-glutamine for Sickle Cell Disease	L-glutamine (Xyndari)	Sickle cell disease (SCD)	Haematology	2018	View \| Download
Lacosamide for primary generalised tonic-clonic seizures – adjunctive therapy	Lacosamide (Vimpat)	Epilepsy	Neurology	2019	View \| Download
LAM-561 in addition to radiation therapy and temozolomide for glioblastoma –adjuvant	2-hydroxyoleic acid (2-OHOA; LP561A1; LAM561) , Radiotherapy , Temozolomide (Temodar; Temodal; SCH 52365)	Glioma	Neurological Cancer	2021	View \| Download
Lanadelumab for prevention of attacks in adults and adolescents with Type I and Type II hereditary angioedema	Lanadelumab (SHP643; TAK-743; Takhzyro)	Hereditary angioedema (HAE)	Genetic Disorders , Immunology	2017	View \| Download
Larotrectinib (LOXO-101) for advanced solid cancers [with an NTRK1, NTRK2, or NTRK3 gene fusion]	Larotrectinib (LOXO-101; Viktravi; larotrectinib sulfate)	Solid tumours	Haematological Cancer and Lymphomas , Oncology	2017	View \| Download
Lasmiditan for acute treatment of migraine	Lasmiditan (COL-144; LY573144)	Migraine	Neurology	2020	View \| Download
Lazertinib with amivantamab and platinum-based chemotherapy for EGFR-mutated locally advanced or metastatic non-small-cell lung cancer after osimertinib failure	Amivantamab (JNJ-6372; JNJ-61186372) , Lazertinib , Platinum-based chemotherapy	Non-small-cell lung cancer (NSCLC)	Lung and Respiratory Cancer	2022	View \| Download
Lebrikizumab for moderate to severe atopic dermatitis	Lebrikizumab (TNX-650; LY3650150)	Atopic dermatitis	Dermatology	2021	View \| Download
Lecanemab for treating early Alzheimer's disease	Lecanemab (BAN2401)	Alzheimer's disease	Neurology	2021	View \| Download