Search All Tech Briefings

Search technology briefings produced by NIHR Innovation Observatory. These are short reports on new or repurposed medicines that we have already sent to our stakeholders. Only those technologies (medicines) that are within the scope of our stakeholders will have a technology briefing available. Search our technology briefings by intervention (drug or device), specific indication (disease or condition), or general therapeutic area.

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Title	Intervention	Indication	Therapeutic Area	Year	Actions
Pirtobrutinib for untreated chronic lymphocytic leukaemia or small lymphocytic lymphoma	Pirtobrutinib (LY3527727; LOXO-305)	Chronic lymphocytic leukaemia (CLL) , Small lymphocytic lymphoma (SLL)	Haematological Cancer and Lymphomas	2023	View \| Download
Pirtobrutinib for chronic lymphocytic leukaemia or small lymphocytic lymphoma after BTK inhibitor therapy	Pirtobrutinib (LY3527727; LOXO-305)	Chronic lymphocytic leukaemia (CLL) , Small lymphocytic lymphoma (SLL)	Haematological Cancer and Lymphomas	2023	View \| Download
Pembrolizumab-vibostolimab with etoposide and platinum chemotherapy for previously untreated extensive-stage small cell lung cancer	Etoposide , Pembrolizumab-vibostolimab (MK-7684; MK7684A; Vibostolimab) , Platinum-based chemotherapy	Small-cell lung cancer (SCLC)	Lung and Respiratory Cancer	2023	View \| Download
Pembrolizumab-vibostolimab for previously untreated non-small-cell lung cancer (NSCLC)	Pembrolizumab-vibostolimab (MK-7684; MK7684A; Vibostolimab)	Non-small-cell lung cancer (NSCLC)	Lung and Respiratory Cancer	2023	View \| Download
Pembrolizumab with radiotherapy and chemotherapy for treating unresectable oesophageal cancer	Chemotherapy , Pembrolizumab (Keytruda; MK-3475) , Radiotherapy	Oesophageal cancer	Head and Neck Cancer	2023	View \| Download
Pembrolizumab with or without olaparib following pembrolizumab with chemoradiation therapy for previously untreated, advanced, stage III non-small-cell lung cancer	Chemoradiotherapy , Olaparib (Lynparza; MK-7339; AZD2281; AZD-2281) , Pembrolizumab (Keytruda; MK-3475)	Non-small-cell lung cancer (NSCLC)	Lung and Respiratory Cancer	2023	View \| Download
Pembrolizumab with olaparib and chemoradiation for previously untreated limited-stage small-cell lung cancer	Chemoradiotherapy , Olaparib (Lynparza; MK-7339; AZD2281; AZD-2281) , Pembrolizumab (Keytruda; MK-3475)	Small-cell lung cancer (SCLC)	Lung and Respiratory Cancer	2023	View \| Download
Pembrolizumab with Lenvatinib and chemotherapy for previously untreated advanced or metastatic gastroesophageal adenocarcinoma	Chemotherapy , Lenvatinib (Kisplyx; E7080; lenvatinib mesilate) , Pembrolizumab (Keytruda; MK-3475)	Gastroesophageal adenocarcinoma	Gastrointestinal Cancer	2023	View \| Download
Pembrolizumab with chemotherapy for treating advanced or recurrent endometrial cancer	Chemotherapy , Pembrolizumab (Keytruda; MK-3475)	Endometrial cancer	Female Reproductive Cancer	2023	View \| Download
Pembrolizumab with chemotherapy for platinum-resistant recurrent ovarian cancer after 1 or 2 therapies	Chemotherapy , Pembrolizumab (Keytruda; MK-3475)	Ovarian cancer	Female Reproductive Cancer	2023	View \| Download