Search All Tech Briefings

Search technology briefings produced by NIHR Innovation Observatory. These are short reports on new or repurposed medicines that we have already sent to our stakeholders. Only those technologies (medicines) that are within the scope of our stakeholders will have a technology briefing available. Search our technology briefings by intervention (drug or device), specific indication (disease or condition), or general therapeutic area.

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Title	Intervention	Indication	Therapeutic Area	Year	Actions
Pridopidine for treating Huntington’s disease in adults	Pridopidine	Huntington's disease	Genetic Disorders , Neurology	2024	View \| Download
Ponatinib for chronic myeloid leukaemia in paediatric patients	Ponatinib (AP24534)	Chronic myeloid leukaemia (CML)	Haematological Cancer and Lymphomas	2024	View \| Download
Pembrolizumab neoadjuvant therapy and as adjuvant therapy with radiotherapy for previously untreated stage III/IVA head and neck squamous cell carcinoma	Pembrolizumab (Keytruda; MK-3475) , Radiotherapy	Head and neck cancer	Head and Neck Cancer	2024	View \| Download
Pembrolizumab adjuvant therapy for locally advanced cutaneous squamous cell carcinoma	Pembrolizumab (Keytruda; MK-3475)	Squamous cell carcinoma (SCC)	Skin Cancer	2024	View \| Download
Pembrolizumab adjuvant for urothelial carcinoma and/or localised muscle invasive bladder cancer	Pembrolizumab (Keytruda; MK-3475)	Urothelial cancer	Urological Cancer	2024	View \| Download
Pegcetacoplan for treating C3 glomerulopathy or immune-complex membranoproliferative glomerulonephritis	Pegcetacoplan (APL-2)	C3 glomerulopathy , Immune-complex membranoproliferative glomerulonephritis	Immunology , Nephrology	2024	View \| Download
Patritumab deruxtecan for previously treated metastatic or locally advanced EGFR mutated non-small-cell lung cancer	Patritumab deruxtecan	Non-small-cell lung cancer (NSCLC)	Lung and Respiratory Cancer	2024	View \| Download
Osmertinib neoadjuvant for treating EGFR mutation positive resectable non-squamous non- small cell lung cancer	Osimertinib (Tagrisso; AZD9291; osimertinib mesylate)	Non-small-cell lung cancer (NSCLC)	Lung and Respiratory Cancer	2024	View \| Download
Olezarsen for treating familial chylomicronaemia syndrome	Olezarsen (ISIS 678354; AKCEA-APOCIII-LRx)	Familial chylomicronaemia syndrome (FCS)	Endocrine Nutritional and Metabolic Disorders , Genetic Disorders	2024	View \| Download
Odevixibat for treating biliary atresia in children following Kasai hepatoportoenterostomy	Odevixibat (A4250)	Biliary atresia	Hepatology	2024	View \| Download