Search All Tech Briefings

Search technology briefings produced by NIHR Innovation Observatory. These are short reports on new or repurposed medicines that we have already sent to our stakeholders. Only those technologies (medicines) that are within the scope of our stakeholders will have a technology briefing available. Search our technology briefings by intervention (drug or device), specific indication (disease or condition), or general therapeutic area.

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Title	Intervention	Indication	Therapeutic Area	Year	Actions
Olaparib in addition to abiraterone for metastatic castration-resistant prostate cancer – First line	Abiraterone acetate (Zytiga; Yonsa) , Olaparib (Lynparza; MK-7339; AZD2281; AZD-2281)	Prostate cancer	Male Reproductive Cancer	2020	View \| Download
Olaparib for Metastatic Pancreatic Cancer with gBRCA Mutation	Olaparib (Lynparza; MK-7339; AZD2281; AZD-2281)	Pancreatic cancer	Gastrointestinal Cancer	2018	View \| Download
Olaparib for BRCAm or ATM mutated metastatic castration-resistant prostate cancer	Olaparib (Lynparza; MK-7339; AZD2281; AZD-2281)	Prostate cancer	Male Reproductive Cancer	2019	View \| Download
Olaparib for BRCA mutated and high risk HER2 negative breast cancer - adjuvant therapy	Olaparib (Lynparza; MK-7339; AZD2281; AZD-2281)	Breast cancer	Breast Cancer	2020	View \| Download
Olaparib (Lynparza) tablets for recurrent platinum-sensitive BRCA-mutated ovarian cancer – maintenance therapy	Olaparib (Lynparza; MK-7339; AZD2281; AZD-2281)	Epithelial ovarian cancer , Fallopian tube cancer , primary peritoneal cancer	Female Reproductive Cancer	2017	View \| Download
Ofatumumab for relapsing multiple sclerosis	Ofatumumab (Arzerra)	Multiple sclerosis (MS)	Neurology	2019	View \| Download
Odevixibat for treating biliary atresia in children following Kasai hepatoportoenterostomy	Odevixibat (A4250)	Biliary atresia	Hepatology	2024	View \| Download
Odevixibat for cholestatic liver disease in Alagille syndrome patients	Odevixibat (A4250)	Alagille syndrome	Genetic Disorders	2022	View \| Download
Ocrelizumab (subcutaneous) for the treatment of primary progressive or relapsing multiple sclerosis	Ocrelizumab (Ocrevus;2H7v114)	Multiple sclerosis (MS)	Neurology	2023	View \| Download
Obinutuzumab with mycophenolate mofetil for treating lupus nephritis	Mycophenolate mofetil (Cellcept) , Obinutuzumab (Gazyvaro; RO5072759; GA101; Afutuzumab)	Lupus nephritis	Immunology , Nephrology	2023	View \| Download