Search All Tech Briefings

Search technology briefings produced by NIHR Innovation Observatory. These are short reports on new or repurposed medicines that we have already sent to our stakeholders. Only those technologies (medicines) that are within the scope of our stakeholders will have a technology briefing available. Search our technology briefings by intervention (drug or device), specific indication (disease or condition), or general therapeutic area.

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Title	Intervention	Indication	Therapeutic Area	Year	Actions
Omecamtiv mecarbil for treating chronic heart failure with reduced ejection fraction	Omecamtiv Mecarbil (AMG 423; CK-1827452)	Heart failure (HF)	Cardiovascular System	2020	View \| Download
Omaveloxolone for the treatment of Friedreich's ataxia	Omaveloxolone	Friedreich's ataxia	Genetic Disorders , Neurology	2023	View \| Download
Omalizumab for chronic rhinosinusitis with nasal polyps	Omalizumab (Xolair)	Rhinosinusitis	Ear Nose and Throat (ENT)	2019	View \| Download
Omalizumab biosimilar for treating chronic spontaneous urticaria	Omalizumab biosimilar	Chronic spontaneous urticaria (CSU)	Dermatology	2023	View \| Download
Olorofim for invasive fungal infections	Olorofim	Fungal infections	Infectious Disease	2023	View \| Download
Olezarsen for treating familial chylomicronaemia syndrome	Olezarsen (ISIS 678354; AKCEA-APOCIII-LRx)	Familial chylomicronaemia syndrome (FCS)	Endocrine Nutritional and Metabolic Disorders , Genetic Disorders	2024	View \| Download
Oleogel-S10 for Inherited Epidermolysis Bullosa	Oleogel-S10 (Episalvan)	Inherited epidermolysis bullosa (EB)	Dermatology , Genetic Disorders	2018	View \| Download
Olaparib monotherapy for BRCA-mutated platinum-sensitive relapsed ovarian, fallopian tube or primary peritoneal cancer	Olaparib (Lynparza; MK-7339; AZD2281; AZD-2281)	Epithelial ovarian cancer , Fallopian tube cancer , primary peritoneal cancer	Female Reproductive Cancer	2019	View \| Download
Olaparib maintenance therapy for non-gBRCA mutated high-grade serous ovarian cancer after platinum-based chemotherapy	Olaparib (Lynparza; MK-7339; AZD2281; AZD-2281)	Non-gBRCA mutated high-grade serous ovarian cancer	Female Reproductive Cancer	2022	View \| Download
Olaparib in combination with bevacizumab for ovarian, fallopian tube or primary peritoneal cancer – maintenance therapy	Bevacizumab (Avastin; R 435; RG 405; RG 435) , Olaparib (Lynparza; MK-7339; AZD2281; AZD-2281)	Fallopian tube cancer , Ovarian cancer , primary peritoneal cancer	Female Reproductive Cancer	2019	View \| Download