Search All Tech Briefings

Search technology briefings produced by NIHR Innovation Observatory. These are short reports on new or repurposed medicines that we have already sent to our stakeholders. Only those technologies (medicines) that are within the scope of our stakeholders will have a technology briefing available. Search our technology briefings by intervention (drug or device), specific indication (disease or condition), or general therapeutic area.

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Title	Intervention	Indication	Therapeutic Area	Year	Actions
Osimertinib maintenance therapy for treating stage III unresectable EGFR mutation positive non-small-cell lung cancer after definitive platinum-based chemoradiation therapy	Osimertinib (Tagrisso; AZD9291; osimertinib mesylate)	Non-small-cell lung cancer (NSCLC)	Lung and Respiratory Cancer	2022	View \| Download
Osimertinib for EGFR-positive non-small cell lung cancer - adjuvant	Osimertinib (Tagrisso; AZD9291; osimertinib mesylate)	Non-small-cell lung cancer (NSCLC)	Lung and Respiratory Cancer	2020	View \| Download
Osimertinib + pemetrexed + carboplatin +/ cisplatin as a first line treatment for non-small cell lung cancer with EGFR mutation	Carboplatin (Paraplatin) , Cisplatin (Platinol) , Osimertinib (Tagrisso; AZD9291; osimertinib mesylate) , Pemetrexed (Alimta; pemetrexed ditromethamine dihydrate; pemetrexed ditrometamol; pemetrexed disodium)	Non-small-cell lung cancer (NSCLC)	Lung and Respiratory Cancer	2023	View \| Download
Osimertinib (Tagrisso) for locally advanced or metastatic non-small cell lung cancer, EGFR mutation positive (Ex19del or L858R) - first line	Osimertinib (Tagrisso; AZD9291; osimertinib mesylate)	Non-small-cell lung cancer (NSCLC)	Lung and Respiratory Cancer	2017	View \| Download
Oral Semaglutide for the treatment of type 2 diabetes mellitus	Semaglutide (Ozempic)	Type 2 diabetes	Endocrine Nutritional and Metabolic Disorders	2018	View \| Download
Oportuzumab monatox for non-muscle invasive bladder cancer - second line	Oportuzumab monatox (Vicinium; VB4-845; Proxinium)	Bladder cancer	Urological Cancer	2020	View \| Download
Opicapone adjuvant for the treatment of idiopathic Parkinson's disease	Opicapone (Ongentys)	Parkinson's disease	Neurology	2023	View \| Download
ONS-5010 for neovascular age-related macular degeneration	ONS-5010	Neovascular age-related macular degeneration	Ophthalmology	2022	View \| Download
Onfekafusp alfa in addition to doxorubicin for advanced or metastatic soft tissue sarcoma – first line	Doxorubicin (Livatag; BA-003; Caelyx; Sarcodoxome; SP-1049C; Resmycin; JNS002; doxorubicin hydrochloride) , Onfekafusp alfa (L19-TNF; Fibromun)	Soft tissue sarcoma	Sarcoma	2019	View \| Download
Ondansetron for treating alcohol use disorder	Ondansetron (Setrodon;TO-2061;AD04)	Alcohol use disorder	Mental and Behavioural Health	2023	View \| Download