Search All Tech Briefings

Search technology briefings produced by NIHR Innovation Observatory. These are short reports on new or repurposed medicines that we have already sent to our stakeholders. Only those technologies (medicines) that are within the scope of our stakeholders will have a technology briefing available. Search our technology briefings by intervention (drug or device), specific indication (disease or condition), or general therapeutic area.

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Title	Intervention	Indication	Therapeutic Area	Year	Actions
Palovarotene for episodic and chronic use in fibrodysplasia ossificans progressiva – first line	Palovarotene (RG-667)	Fibrodysplasia ossificans progressiva	Musculoskeletal System	2019	View \| Download
Palbociclib with trastuzumab with or without pertuzumab and endocrine therapy for HR+/HER2+ metastatic breast cancer	Palbociclib (Ibrance; PD-0332991) , Trastuzumab (Herceptin; RG-597)	Breast cancer	Breast Cancer	2023	View \| Download
Palbociclib for breast cancer - post neoadjuvant therapy	Palbociclib (Ibrance; PD-0332991)	Breast cancer	Breast Cancer	2020	View \| Download
Paclitaxel with Encequidar for advanced breast cancer	Encequidar (HM-30181) , Paclitaxel (Taxol; paclitaxel albumin)	Breast cancer	Breast Cancer	2022	View \| Download
Ozanimod for moderate to severe ulcerative colitis	Ozanimod (RPC1063; Zeposia; ozanimod hydrochloride)	Ulcerative colitis	Gastroenterology	2020	View \| Download
Oxybutynin hydrochloride for treating neurogenic detrusor overactivity	Oxybutynin hydrochloride (Vesoxx)	Neurogenic detrusor overactivity	Neurology , Urology	2022	View \| Download
OTL-200 for Metachromatic Leukodystrophy	OTL-200 (GSK-2696274)	Metachromatic leukodystrophy (MLD)	Endocrine Nutritional and Metabolic Disorders , Genetic Disorders	2019	View \| Download
OTL-103 for Wiskott-Aldrich syndrome	OTL-103 (GSK-2696275)	Wiskott-Aldrich syndrome (WAS)	Genetic Disorders , Immunology	2020	View \| Download
Otilimab in combination with conventional synthetic DMARDs for treating rheumatoid arthritis	Otilimab	Rheumatoid arthritis	Rheumatology	2022	View \| Download
Osmertinib neoadjuvant for treating EGFR mutation positive resectable non-squamous non- small cell lung cancer	Osimertinib (Tagrisso; AZD9291; osimertinib mesylate)	Non-small-cell lung cancer (NSCLC)	Lung and Respiratory Cancer	2024	View \| Download