Search All Tech Briefings

Search technology briefings produced by NIHR Innovation Observatory. These are short reports on new or repurposed medicines that we have already sent to our stakeholders. Only those technologies (medicines) that are within the scope of our stakeholders will have a technology briefing available. Search our technology briefings by intervention (drug or device), specific indication (disease or condition), or general therapeutic area.

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Title	Intervention	Indication	Therapeutic Area	Year	Actions
PEGPH20 in addition to Nab-paclitaxel and Gemcitabine for Metastatic Pancreatic Ductal Adenocarcinoma	Gemcitabine (Gemzar; gemcitabine hydrochloride) , Nab-Paclitaxel (Abraxane; ABI 007; ABI-007) , Pegvorhyaluronidase alfa (PEGPH20)	Pancreatic cancer	Gastrointestinal Cancer	2018	View \| Download
Pegcetacoplan for treating geographic atrophy	Pegcetacoplan (APL-2)	Geographic atrophy	Ophthalmology	2021	View \| Download
Pegcetacoplan for treating C3 glomerulopathy or immune-complex membranoproliferative glomerulonephritis	Pegcetacoplan (APL-2)	C3 glomerulopathy , Immune-complex membranoproliferative glomerulonephritis	Immunology , Nephrology	2024	View \| Download
Pegcetacoplan for treating amyotrophic lateral sclerosis	Pegcetacoplan (APL-2)	Amyotrophic lateral sclerosis	Neurology	2023	View \| Download
Pegcetacoplan (APL-2) for paroxysmal nocturnal haemoglobinuria	Pegcetacoplan (APL-2)	Paroxysmal nocturnal haemoglobinuria (PNH)	Haematology	2019	View \| Download
Pegargiminase in addition to pemetrexed and cisplatin for advanced malignant pleural mesothelioma – first line	Cisplatin (Platinol) , Pegargiminase (ADI-PEG 20) , Pemetrexed (Alimta; pemetrexed ditromethamine dihydrate; pemetrexed ditrometamol; pemetrexed disodium)	Malignant pleural mesothelioma (MPM)	Lung and Respiratory Cancer	2018	View \| Download
Patritumab deruxtecan for previously treated metastatic or locally advanced EGFR mutated non-small-cell lung cancer	Patritumab deruxtecan	Non-small-cell lung cancer (NSCLC)	Lung and Respiratory Cancer	2024	View \| Download
Parsaclisib for marginal zone lymphoma – relapsed or refractory	Parsaclisib (INCB050465)	Marginal zone lymphoma (MZL)	Haematological Cancer and Lymphomas	2021	View \| Download
Pariglasgene brecaparvovec for treating glycogen storage disease type 1a	Pariglasgene brecaparvovec	Glycogen storage disease type 1a	Endocrine Nutritional and Metabolic Disorders	2023	View \| Download
Palovarotene for flare-ups in fibrodysplasia ossificans progressiva – first line	Palovarotene (RG-667)	Fibrodysplasia ossificans progressiva	Musculoskeletal System	2019	View \| Download