Search All Tech Briefings

Search technology briefings produced by NIHR Innovation Observatory. These are short reports on new or repurposed medicines that we have already sent to our stakeholders. Only those technologies (medicines) that are within the scope of our stakeholders will have a technology briefing available. Search our technology briefings by intervention (drug or device), specific indication (disease or condition), or general therapeutic area.

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Title	Intervention	Indication	Therapeutic Area	Year	Actions
Eryaspase in addition to chemotherapy for treating advanced or metastatic pancreatic cancer – second-line	Eryaspase (Graspa; ERY001) , FOLFOX4 , Gemcitabine (Gemzar; gemcitabine hydrochloride)	Pancreatic cancer	Gastrointestinal Cancer	2020	View \| Download
Favezelimab-pembrolizumab for treating metastatic PD-L1 positive colorectal cancer	Favezelimab-pembrolizumab	Colorectal cancer	Gastrointestinal Cancer , Oncology	2023	View \| Download
Fruquintinib for treating refractory metastatic colorectal cancer	Fruquintinib (Elunate; TAK113; HMPL013)	Colorectal cancer	Gastrointestinal Cancer , Oncology	2023	View \| Download
Infigratinib for unresectable locally advanced or metastatic cholangiocarinoma with FGFR2 rearrangements – second line	Infigratinib (BGJ398; BGJ-398; Truseltiq)	Cholangiocarcinoma	Gastrointestinal Cancer	2021	View \| Download
Intravenous Doxorubicin Nanoparticles for Advanced Hepatocellular Carcinoma	Doxorubicin (Livatag; BA-003; Caelyx; Sarcodoxome; SP-1049C; Resmycin; JNS002; doxorubicin hydrochloride)	Hepatocellular carcinoma (HCC)	Gastrointestinal Cancer	2017	View \| Download
Irinotecan liposome injection with oxaliplatin, 5-fluorouracil and leucovorin for previously untreated metastatic pancreatic cancer	5-Fluorouracil , Irinotecan liposome injection , Leucovorin , Oxaliplatin	Pancreatic cancer	Gastrointestinal Cancer	2024	View \| Download
Ivosidenib for previously treated advanced cholangiocarcinoma	Ivosidenib (Tibsovo; AG-120)	Cholangiocarcinoma	Gastrointestinal Cancer	2022	View \| Download
Lenvatinib and pembrolizumab with transarterial chemoembolisation for treating hepatocellular carcinoma	Lenvatinib (Kisplyx; E7080; lenvatinib mesilate) , Pembrolizumab (Keytruda; MK-3475)	Hepatocellular carcinoma (HCC)	Gastrointestinal Cancer	2022	View \| Download
Lenvatinib in combination with pembrolizumab for advanced/unresectable hepatocellular carcinoma – first-line	Lenvatinib (Kisplyx; E7080; lenvatinib mesilate) , Pembrolizumab (Keytruda; MK-3475)	Hepatocellular carcinoma (HCC)	Gastrointestinal Cancer	2021	View \| Download
Nab-paclitaxel in Combination with Gemcitabine for Resected Pancreatic Ductal Adenocarcinoma - Adjuvant Therapy	Gemcitabine (Gemzar; gemcitabine hydrochloride) , Nab-Paclitaxel (Abraxane; ABI 007; ABI-007)	Pancreatic cancer	Gastrointestinal Cancer	2017	View \| Download