Search All Tech Briefings

Search technology briefings produced by NIHR Innovation Observatory. These are short reports on new or repurposed medicines that we have already sent to our stakeholders. Only those technologies (medicines) that are within the scope of our stakeholders will have a technology briefing available. Search our technology briefings by intervention (drug or device), specific indication (disease or condition), or general therapeutic area.

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Title	Intervention	Indication	Therapeutic Area	Year	Actions
Selinexor in combination with low-dose dexamethasone for penta-refractory multiple myeloma	Dexamethasone (dexamethasone sodium metasulfobenzoate) , Selinexor (KPT-330; Xpovio)	Multiple myeloma (MM)	Haematological Cancer and Lymphomas	2018	View \| Download
Selinexor in addition to bortezomib and low-dose dexamethasone for relapsed or refractory multiple myeloma	Bortezomib (Velcade; bortezomib mannitol boronic ester) , Dexamethasone (dexamethasone sodium metasulfobenzoate) , Selinexor (KPT-330; Xpovio)	Multiple myeloma (MM)	Haematological Cancer and Lymphomas	2020	View \| Download
Sabatolimab in addition to azacitidine for myelodysplastic syndromes – first-line	Azacitidine (Vidaza; CC-486) , Sabatolimab (MBG453)	Chronic myelomonocytic leukaemia (CMML) , Myelodysplastic syndrome (MDS)	Haematological Cancer and Lymphomas	2021	View \| Download
Ropeginterferon alfa-2b for polycythaemia vera without symptomatic splenomegaly	Ropeginterferon alfa 2-b (P-1101; AOP2014; Pegylated-Proline-interferon alpha-2b)	Polycythaemia vera	Haematological Cancer and Lymphomas	2019	View \| Download
Rigosertib for myelodysplastic syndrome - second line	Rigosertib (Estybon; ON-01910.Na)	Myelodysplastic syndrome (MDS)	Haematological Cancer and Lymphomas	2020	View \| Download
Resminostat for maintenance treatment of patients with advanced stage mycosis fungoides or Sézary syndrome	Resminostat (4SC-201)	Cutaneous T-cell lymphoma (CTCL) , Mycosis fungoides or sezary syndrome	Haematological Cancer and Lymphomas , Skin Cancer	2024	View \| Download
REGN5458 for relapsed or refractory multiple myeloma	REGN5458	Multiple myeloma (MM)	Haematological Cancer and Lymphomas	2022	View \| Download
Quizartinib with chemotherapy for FLT3-ITD positive acute myeloid leukaemia	Quizartinib (AC220)	Acute myeloid leukaemia (AML)	Haematological Cancer and Lymphomas	2021	View \| Download
Ponatinib for chronic myeloid leukaemia in paediatric patients	Ponatinib (AP24534)	Chronic myeloid leukaemia (CML)	Haematological Cancer and Lymphomas	2024	View \| Download
Pomalidomide (Imnovid) with bortezomib and dexamethasone for relapsed or refractory multiple myeloma‐ second line and beyond	Bortezomib (Velcade; bortezomib mannitol boronic ester) , Dexamethasone (dexamethasone sodium metasulfobenzoate) , Pomalidomide (Imnovid; CC-4047; Pomalyst)	Multiple myeloma (MM)	Haematological Cancer and Lymphomas	2017	View \| Download