Search All Tech Briefings

Search technology briefings produced by NIHR Innovation Observatory. These are short reports on new or repurposed medicines that we have already sent to our stakeholders. Only those technologies (medicines) that are within the scope of our stakeholders will have a technology briefing available. Search our technology briefings by intervention (drug or device), specific indication (disease or condition), or general therapeutic area.

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Title	Intervention	Indication	Therapeutic Area	Year	Actions
Ruxolitinib for treating chronic graft versus host disease after allogeneic stem cell transplant in paediatric patients	Ruxolitinib (Jakavi; INCB018424; CTP-543; ruxolitinib phosphate)	Graft versus host disease (GvHD)	Immunology	2023	View \| Download
Ruxolitinib for grades II-IV treatment-naïve or steroid-refractory acute graft versus host disease	Ruxolitinib (Jakavi; INCB018424; CTP-543; ruxolitinib phosphate)	Graft versus host disease (GvHD)	Immunology	2023	View \| Download
Rilzabrutinib for treating persistent or chronic immune thrombocytopenia	Rilzabrutinib	Immune thrombocytopenia (ITP)	Haematology , Immunology	2023	View \| Download
Resmetirom for non-alcoholic steatohepatitis	Resmetirom (MGL-3196)	Non-alcoholic steatohepatitis (NASH)	Hepatology	2023	View \| Download
Repotrectinib for treating advanced or metastatic nonsmall-cell lung cancer with ROS1-postive mutation	Repotrectinib (TPX 0005)	Non-small-cell lung cancer (NSCLC)	Lung and Respiratory Cancer	2023	View \| Download
Remibrutinib for treating chronic spontaneous urticaria inadequately controlled by H1-antihistamines	Remibrutini (LOU064)	Chronic spontaneous urticaria (CSU)	Dermatology	2023	View \| Download
Ravulizumab for treating thrombotic microangiopathies following haematopoietic stem cell transplantation in children	Ravulizumab (ALXN1210; Ultomiris)	Thrombotic microangiopathies	Haematology	2023	View \| Download
Pylera with omeprazole for treating helicobacter pylori associated ulcers	Omeprazole (Yosprala;PA32540;Omeprazole magnesium;Omeprazole sodium , Pylera (BLI-1300;FP-110;Metronidazole benzoate)	Helicobacter pylori	Gastroenterology	2023	View \| Download
PXT3003 for treating Charcot-Marie-Tooth disease type 1A	PXT-3003 (fixed dose combination: baclofen; Naltrexone hydrochloride; sorbitol)	Charcot-Marie-Tooth disease	Genetic Disorders , Neurology	2023	View \| Download
Pitolisant for treating narcolepsy in children and adolescents	Pitolisant (Wakix;BF 2649)	Narcolepsy	Neurology	2023	View \| Download