Search All Tech Briefings

Search technology briefings produced by NIHR Innovation Observatory. These are short reports on new or repurposed medicines that we have already sent to our stakeholders. Only those technologies (medicines) that are within the scope of our stakeholders will have a technology briefing available. Search our technology briefings by intervention (drug or device), specific indication (disease or condition), or general therapeutic area.

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Title	Intervention	Indication	Therapeutic Area	Year	Actions
siG12D‐LODER in addition to standard chemotherapy for locally advanced pancreatic cancer	Gemcitabine (Gemzar; gemcitabine hydrochloride) , Nab-Paclitaxel (Abraxane; ABI 007; ABI-007) , siG12D-LODER	Pancreatic cancer	Gastrointestinal Cancer	2018	View \| Download
Seviprotimut-L for Malignant Melanoma after Surgery	Seviprotimut-L (POL-103A)	Melanoma	Skin Cancer	2018	View \| Download
Setmelanotide for treating obesity caused by rare genetic disorders in children aged 2 to 6 years	Setmelanotide (RM-493)	Obesity	Endocrine Nutritional and Metabolic Disorders	2022	View \| Download
Setmelanotide for treating acquired hypothalamic obesity in people 4 years and older	Setmelanotide (RM-493)	Hypothalamic obesity	Endocrine Nutritional and Metabolic Disorders	2024	View \| Download
Setmelanotide for rare genetic obesity due to leptin receptor deficiency	Setmelanotide (RM-493)	Obesity due to Leptin receptor deficiency	Endocrine Nutritional and Metabolic Disorders	2019	View \| Download
Setmelanotide for pro-opiomelanocortin deficiency obesity	Setmelanotide (RM-493)	Obesity due to pro-opiomelanocortin deficiency	Endocrine Nutritional and Metabolic Disorders	2017	View \| Download
Setmelanotide for obesity in Bardet-Biedl syndrome and Alstrom syndrome	Setmelanotide (RM-493)	Hyperphagia , Obesity	Endocrine Nutritional and Metabolic Disorders , Gastroenterology , Genetic Disorders	2021	View \| Download
Serplulimab with chemotherapy for treating previously untreated extensive stage small-cell lung cancer	Serplulimab (HLX10)	Small-cell lung cancer (SCLC)	Lung and Respiratory Cancer	2023	View \| Download
Semaglutide for treating peripheral arterial disease (PAD) and type 2 diabetes	Semaglutide (Ozempic)	Peripheral arterial disease (PAD) , Type 2 diabetes	Cardiovascular System , Endocrine Nutritional and Metabolic Disorders	2022	View \| Download
Semaglutide for treating overweight or obesity with cardiovascular disease	Semaglutide (Ozempic)	Cardiovascular disease (CVD) , Obesity	Cardiovascular System , Endocrine Nutritional and Metabolic Disorders	2023	View \| Download