Search All Tech Briefings

Search technology briefings produced by NIHR Innovation Observatory. These are short reports on new or repurposed medicines that we have already sent to our stakeholders. Only those technologies (medicines) that are within the scope of our stakeholders will have a technology briefing available. Search our technology briefings by intervention (drug or device), specific indication (disease or condition), or general therapeutic area.

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Title	Intervention	Indication	Therapeutic Area	Year	Actions
Daratumumab in addition to pomalidomide and dexamethasone for relapsed or refractory multiple myeloma	Daratumumab (Darzalex; JNJ-54767414) , Dexamethasone (dexamethasone sodium metasulfobenzoate) , Pomalidomide (Imnovid; CC-4047; Pomalyst)	Multiple myeloma (MM)	Haematological Cancer and Lymphomas	2020	View \| Download
Daratumumab in addition to Bortezomib, Thalidomide and Dexamethasone for newly diagnosed Multiple Myeloma	Bortezomib (Velcade; bortezomib mannitol boronic ester) , Daratumumab (Darzalex; JNJ-54767414) , Dexamethasone (dexamethasone sodium metasulfobenzoate) , Thalidomide (Taldo)	Multiple myeloma (MM)	Haematological Cancer and Lymphomas	2018	View \| Download
Daratumumab in addition to bortezomib, lenalidomide and dexamethasone for multiple myeloma – first line	Bortezomib (Velcade; bortezomib mannitol boronic ester) , Daratumumab (Darzalex; JNJ-54767414) , Dexamethasone (dexamethasone sodium metasulfobenzoate) , Lenalidomide (Revlimid)	Multiple myeloma (MM)	Haematological Cancer and Lymphomas	2020	View \| Download
Daratumumab for the treating high-risk smouldering multiple myeloma	Daratumumab (Darzalex; JNJ-54767414)	Multiple myeloma (MM)	Haematological Cancer and Lymphomas	2022	View \| Download
Daratumumab (subcutaneous injection) for multiple myeloma	Daratumumab (Darzalex; JNJ-54767414)	Multiple myeloma (MM)	Haematological Cancer and Lymphomas	2019	View \| Download
Daratumumab (Darzalex) with lenalidomide and dexamethasone for multiple myeloma – first line	Daratumumab (Darzalex; JNJ-54767414) , Dexamethasone (dexamethasone sodium metasulfobenzoate) , Lenalidomide (Revlimid)	Multiple myeloma (MM)	Haematological Cancer and Lymphomas	2017	View \| Download
Crizotinib for paediatric ALK-positive anaplastic large cell lymphoma or inflammatory myofibroblastic tumour	Crizotinib (Xalkori; PF-02341066; Xalkor)	Anaplastic large cell lymphoma (ALCL) , Myofibroblastic tumour	Haematological Cancer and Lymphomas	2021	View \| Download
Ciltacabtagene autoleucel for relapsed and refractory multiple myeloma	Ciltacabtagene Autoleucel (JNJ-68284528; LCAR-B38M CAR-T cell therapy; LCAR-B38M; JNJ 4528)	Multiple myeloma (MM)	Haematological Cancer and Lymphomas , Haematology	2021	View \| Download
CC-486 for maintenance therapy in acute myeloid leukaemia	Azacitidine (Vidaza; CC-486)	Acute myeloid leukaemia (AML)	Haematological Cancer and Lymphomas	2020	View \| Download
CC-486 for angioimmunoblastic T-cell lymphoma	Azacitidine (Vidaza; CC-486)	Angioimmunoblastic T-cell Lymphoma (AITL)	Haematological Cancer and Lymphomas	2020	View \| Download