Search All Tech Briefings

Search technology briefings produced by NIHR Innovation Observatory. These are short reports on new or repurposed medicines that we have already sent to our stakeholders. Only those technologies (medicines) that are within the scope of our stakeholders will have a technology briefing available. Search our technology briefings by intervention (drug or device), specific indication (disease or condition), or general therapeutic area.

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Title	Intervention	Indication	Therapeutic Area	Year	Actions
Elexacaftor/tezacaftor/ivacaftor and ivacaftor for treating cystic fibrosis without an F508del mutation and with an ELX/TEZ/IVA-responsive mutation in the CFTR gene in patients aged 6 years and older	Ivacaftor (Kalydeco; VX-770) , Kaftrio (fixed dose combination: Elexacaftor; Tezacaftor; Ivacaftor)	Cystic fibrosis	Genetic Disorders , Respiratory System	2023	View \| Download
Elafibranor for previously treated primary biliary cholangitis	Elafibranor (GFT-505)	Primary biliary cholangitis (PBC)	Hepatology	2023	View \| Download
Eflornithine with lomustine for treating recurrent anaplastic astrocytoma	Eflornithine (CPP-1X; Difluoromethylornithine; DFMO; Vaniqa; eflornithine hydrochloride monohydrate) , lomustine	Anaplastic astrocytoma	Neurological Cancer	2023	View \| Download
Efgartigimod PH20 SC for treating chronic inflammatory demyelinating polyradiculoneuropathy	Efgartigimod PH20 SC	Chronic inflammatory demyelinating polyradiculoneuropathy	Neurology	2023	View \| Download
Efgartigimod PH20 SC for adults with primary immune thrombocytopenia	Efgartigimod PH20 SC	Immune thrombocytopenia (ITP)	Haematology , Immunology	2023	View \| Download
Efgartigimod alfa for treating pemphigus vulgaris or pemphigus foliaceus	Efgartigimod alfa (ARGX-113)	Pemphigus foliaceus , Pemphigus vulgaris	Dermatology , Immunology	2023	View \| Download
Efgartigimod alfa (subcutaneous injection) for treating generalised myasthenia gravis	Efgartigimod alfa (ARGX-113)	Myasthenia gravis (MG)	Musculoskeletal System	2023	View \| Download
Edaravone for treating amyotrophic lateral sclerosis	Edaravone oral (FNP1222)	Amyotrophic lateral sclerosis	Neurology	2023	View \| Download
Durvalumab with fluorouracil, leucovorin, oxaliplatin and docetaxel chemotherapy for neoadjuvant and adjuvant treatment of resectable gastric and gastro-oesophageal junction cancer	5-Fluorouracil , Docetaxel (Taxotere; docetaxel trihydrate; docetaxel anhydrous) , Durvalumab (Imfinzi; MEDI4736; MEDI-4736; MEDI 4736) , Leucovorin , Oxaliplatin	Gastro-oesophageal junction cancer	Gastrointestinal Cancer	2023	View \| Download
Durvalumab with carboplatin and paclitaxel with or without olaparib for newly diagnosed advanced or reccurent endometrial cancer	Carboplatin (Paraplatin) , Durvalumab (Imfinzi; MEDI4736; MEDI-4736; MEDI 4736) , Olaparib (Lynparza; MK-7339; AZD2281; AZD-2281) , Paclitaxel (Taxol; paclitaxel albumin)	Endometrial cancer	Female Reproductive Cancer	2023	View \| Download