Search All Tech Briefings

Search technology briefings produced by NIHR Innovation Observatory. These are short reports on new or repurposed medicines that we have already sent to our stakeholders. Only those technologies (medicines) that are within the scope of our stakeholders will have a technology briefing available. Search our technology briefings by intervention (drug or device), specific indication (disease or condition), or general therapeutic area.

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Title	Intervention	Indication	Therapeutic Area	Year	Actions
Pariglasgene brecaparvovec for treating glycogen storage disease type 1a	Pariglasgene brecaparvovec	Glycogen storage disease type 1a	Endocrine Nutritional and Metabolic Disorders	2023	View \| Download
Pegcetacoplan for treating amyotrophic lateral sclerosis	Pegcetacoplan (APL-2)	Amyotrophic lateral sclerosis	Neurology	2023	View \| Download
Pembrolizumab and chemoradiation for treating muscle-invasive, non-metastatic bladder cancer	Chemoradiotherapy , Pembrolizumab (Keytruda; MK-3475)	Bladder cancer	Urological Cancer	2023	View \| Download
Pembrolizumab with Bacillus Calmette-Guerin for treating high-risk non-muscle invasive bladder cancer	Bacillus Calmette-Guerin (BCG; BCG Tokyo-172; OncoTICE) , Pembrolizumab (Keytruda; MK-3475)	Bladder cancer	Urological Cancer	2023	View \| Download
Pembrolizumab with chemotherapy for HR+/HER2- locally recurrent inoperable or metastatic breast cancer	Chemotherapy , Pembrolizumab (Keytruda; MK-3475)	Breast cancer	Breast Cancer	2023	View \| Download
Pembrolizumab with chemotherapy for platinum-resistant recurrent ovarian cancer after 1 or 2 therapies	Chemotherapy , Pembrolizumab (Keytruda; MK-3475)	Ovarian cancer	Female Reproductive Cancer	2023	View \| Download
Pembrolizumab with chemotherapy for treating advanced or recurrent endometrial cancer	Chemotherapy , Pembrolizumab (Keytruda; MK-3475)	Endometrial cancer	Female Reproductive Cancer	2023	View \| Download
Pembrolizumab with Lenvatinib and chemotherapy for previously untreated advanced or metastatic gastroesophageal adenocarcinoma	Chemotherapy , Lenvatinib (Kisplyx; E7080; lenvatinib mesilate) , Pembrolizumab (Keytruda; MK-3475)	Gastroesophageal adenocarcinoma	Gastrointestinal Cancer	2023	View \| Download
Pembrolizumab with olaparib and chemoradiation for previously untreated limited-stage small-cell lung cancer	Chemoradiotherapy , Olaparib (Lynparza; MK-7339; AZD2281; AZD-2281) , Pembrolizumab (Keytruda; MK-3475)	Small-cell lung cancer (SCLC)	Lung and Respiratory Cancer	2023	View \| Download
Pembrolizumab with or without olaparib following pembrolizumab with chemoradiation therapy for previously untreated, advanced, stage III non-small-cell lung cancer	Chemoradiotherapy , Olaparib (Lynparza; MK-7339; AZD2281; AZD-2281) , Pembrolizumab (Keytruda; MK-3475)	Non-small-cell lung cancer (NSCLC)	Lung and Respiratory Cancer	2023	View \| Download