Search All Tech Briefings

Search technology briefings produced by NIHR Innovation Observatory. These are short reports on new or repurposed medicines that we have already sent to our stakeholders. Only those technologies (medicines) that are within the scope of our stakeholders will have a technology briefing available. Search our technology briefings by intervention (drug or device), specific indication (disease or condition), or general therapeutic area.

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Title	Intervention	Indication	Therapeutic Area	Year	Actions
Pembrolizumab with radiotherapy and chemotherapy for treating unresectable oesophageal cancer	Chemotherapy , Pembrolizumab (Keytruda; MK-3475) , Radiotherapy	Oesophageal cancer	Head and Neck Cancer	2023	View \| Download
Pembrolizumab-vibostolimab for previously untreated non-small-cell lung cancer (NSCLC)	Pembrolizumab-vibostolimab (MK-7684; MK7684A; Vibostolimab)	Non-small-cell lung cancer (NSCLC)	Lung and Respiratory Cancer	2023	View \| Download
Pembrolizumab-vibostolimab with etoposide and platinum chemotherapy for previously untreated extensive-stage small cell lung cancer	Etoposide , Pembrolizumab-vibostolimab (MK-7684; MK7684A; Vibostolimab) , Platinum-based chemotherapy	Small-cell lung cancer (SCLC)	Lung and Respiratory Cancer	2023	View \| Download
Pirtobrutinib for chronic lymphocytic leukaemia or small lymphocytic lymphoma after BTK inhibitor therapy	Pirtobrutinib (LY3527727; LOXO-305)	Chronic lymphocytic leukaemia (CLL) , Small lymphocytic lymphoma (SLL)	Haematological Cancer and Lymphomas	2023	View \| Download
Pirtobrutinib for untreated chronic lymphocytic leukaemia or small lymphocytic lymphoma	Pirtobrutinib (LY3527727; LOXO-305)	Chronic lymphocytic leukaemia (CLL) , Small lymphocytic lymphoma (SLL)	Haematological Cancer and Lymphomas	2023	View \| Download
Pitolisant for treating narcolepsy in children and adolescents	Pitolisant (Wakix;BF 2649)	Narcolepsy	Neurology	2023	View \| Download
PXT3003 for treating Charcot-Marie-Tooth disease type 1A	PXT-3003 (fixed dose combination: baclofen; Naltrexone hydrochloride; sorbitol)	Charcot-Marie-Tooth disease	Genetic Disorders , Neurology	2023	View \| Download
Pylera with omeprazole for treating helicobacter pylori associated ulcers	Omeprazole (Yosprala;PA32540;Omeprazole magnesium;Omeprazole sodium , Pylera (BLI-1300;FP-110;Metronidazole benzoate)	Helicobacter pylori	Gastroenterology	2023	View \| Download
Ravulizumab for treating thrombotic microangiopathies following haematopoietic stem cell transplantation in children	Ravulizumab (ALXN1210; Ultomiris)	Thrombotic microangiopathies	Haematology	2023	View \| Download
Remibrutinib for treating chronic spontaneous urticaria inadequately controlled by H1-antihistamines	Remibrutini (LOU064)	Chronic spontaneous urticaria (CSU)	Dermatology	2023	View \| Download