Search All Tech Briefings

Search technology briefings produced by NIHR Innovation Observatory. These are short reports on new or repurposed medicines that we have already sent to our stakeholders. Only those technologies (medicines) that are within the scope of our stakeholders will have a technology briefing available. Search our technology briefings by intervention (drug or device), specific indication (disease or condition), or general therapeutic area.

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Title	Intervention	Indication	Therapeutic Area	Year	Actions
Pembrolizumab adjuvant therapy for locally advanced cutaneous squamous cell carcinoma	Pembrolizumab (Keytruda; MK-3475)	Squamous cell carcinoma (SCC)	Skin Cancer	2024	View \| Download
Pembrolizumab neoadjuvant therapy and as adjuvant therapy with radiotherapy for previously untreated stage III/IVA head and neck squamous cell carcinoma	Pembrolizumab (Keytruda; MK-3475) , Radiotherapy	Head and neck cancer	Head and Neck Cancer	2024	View \| Download
Pembrolizumab with lenvatinib and chemotherapy for the treatment of metastatic squamous cell oesophageal carcinoma	Chemotherapy , Lenvatinib (Kisplyx; E7080; lenvatinib mesilate) , Pembrolizumab (Keytruda; MK-3475)	Squamous cell oesophageal carcinoma	Head and Neck Cancer	2024	View \| Download
Pertuzumab biosimilar with trastuzumab and chemotherapy neoadjuvant and adjuvant therapy for early stage and locally advanced HER2-positive breast cancer	Chemotherapy , Pertuzumab biosimilar , Trastuzumab (Herceptin; RG-597)	Breast cancer	Breast Cancer	2024	View \| Download
Pirtobrutinib for previously treated Bruton tyrosine kinase inhibitor naïve mantle cell lymphoma	Pirtobrutinib (LY3527727; LOXO-305)	Mantle cell lymphoma	Haematological Cancer and Lymphomas	2024	View \| Download
Ponatinib for chronic myeloid leukaemia in paediatric patients	Ponatinib (AP24534)	Chronic myeloid leukaemia (CML)	Haematological Cancer and Lymphomas	2024	View \| Download
Pridopidine for treating Huntington’s disease in adults	Pridopidine	Huntington's disease	Genetic Disorders , Neurology	2024	View \| Download
Resminostat for maintenance treatment of patients with advanced stage mycosis fungoides or Sézary syndrome	Resminostat (4SC-201)	Cutaneous T-cell lymphoma (CTCL) , Mycosis fungoides or sezary syndrome	Haematological Cancer and Lymphomas , Skin Cancer	2024	View \| Download
Retifanlimab with carboplatin with paclitaxel for treating locally advanced or metastatic squamous cell anal carcinoma	Carboplatin (Paraplatin) , Paclitaxel (Taxol; paclitaxel albumin) , Retifanlimab (INCMGA00012; MGA-012)	Squamous cell anal carcinoma	Gastrointestinal Cancer	2024	View \| Download
Retifanlimab with chemotherapy for previously untreated metastatic non-small-cell lung cancer	Endocrine therapy , Ribociclib (Kisqali; LEE-011; ribociclib succinate)	Breast cancer , Non-small-cell lung cancer (NSCLC)	Breast Cancer , Lung and Respiratory Cancer	2024	View \| Download